Kelly Chien, MD, assistant professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX , discusses how disparities in access to care, resources, and molecular testing impact outcomes for patients with acute myeloid leukemia (AML) across diverse populations. The conversation explores geographic and institutional differences in the standard of care, the consequences of unequal access to genetic testing on treatment planning, and how these disparities affect prognosis. Dr. Chien also highlights current efforts within the medical community to confront racial, ethnic, and socioeconomic inequities in AML care, while identifying critical unanswered questions that must be addressed to ensure more equitable outcomes for all patients.