Elizabeth Brem, MD, of UCI Health, explains how the OLYMPIA-1 study, evaluating odronextamab versus investigator’s choice in patients with previously untreated follicular lymphoma aligns with a new paradigm shift. Dr. Brem outlines the study’s potential impact on therapeutic strategies. She also offers expert perspectives on future decision-making between bispecific antibodies and chimeric antigen receptor T-cell therapies, ad how to sequence the influx of new therapies.