Dr. Cortes and colleagues presented the research during the 2023 American Society of Clinical Oncology Annual Meeting. The study included patients who received at least two prior lines of therapy, including a BTK inhibitor. Older adult patients with newly diagnosed Ph- ALL may benefit from this combination therapy. In this poor-risk population of patients, 73% responded to the triplet. Researchers reported real-world patterns and outcomes by race and line of therapy in a poster presentation at ASCO. However, more than half (53%) of patients discontinued at least one venetoclax regimen. Dr. Hill and colleagues presented their research on the CAR-T manufacturing approach during the 2023 ASCO meeting. The study is currently enrolling patients who have previously received a Bruton tyrosine kinase inhibitor.